MK677

01/01/2025

MK-677 (Ibutamoren): Usage Guide for Growth and Appetite

Recommended Dosage:

  • Low Dose: 5 mg daily
  • Average Dose: 10 mg daily
  • High Dose: 20-30 mg daily
  • Take capsules before your first meal of the day.

Monitoring Blood Glucose:

If you're using a blood glucose monitor:

  1. Test Weekly: Check fasted glucose levels in the morning, before eating.
  2. Glucose Level Guide:
    • Ideal for gains: 70-85 mg/dl
    • Healthy: 85-89 mg/dl
    • Fine but monitor: 90-100 mg/dl
    • At risk of diabetes: 100-125 mg/dl
    • Diabetes: 126 mg/dl or above

If Glucose Levels Are Too High:

  • Use Berberine or Metformin (refer to specific guides for dosage).
  • Consider SGLT-2 or DPP-4 inhibitors if further intervention is needed.
  • Lower the MK-677 dose if necessary.
  • Discontinue MK-677 if glucose remains elevated.

Using MK-677 for Fat Loss:

  • Pro: MK-677 promotes fat loss through growth hormone (GH) benefits.
  • Con: It may significantly increase appetite, which can make fat loss more challenging.

Dosing for Women:

  • Women can tolerate MK-677 well, sometimes better than men.
  • A good dose range is 10-25 mg daily.

Blood Work Considerations:

  • Blood work is not mandatory but is recommended if you can afford it.
  • It's more important to track fasted blood glucose levels while using MK-677.

Test Base Requirement:

  • Not needed: At recommended doses, MK-677 is unlikely to cause significant testosterone suppression.
  • Higher doses (>20 mg daily): Increased risk of suppression via a prolactin feedback loop.

Post Cycle Therapy (PCT) After MK-677:

  • Testosterone: PCT is generally not required, as suppression is unlikely at recommended doses.
  • Growth Hormone: PCT for HGH can be done by fasting for 5 days (water only) to quickly restore natural HGH production after stopping MK-677.